Section Edited by Claudia Palena, PhD and Eric Tartour, MD, PhD
Tumor antigens, innate and adaptive anti-tumor immune mechanisms, immune regulation, immune response, cancer and inflammation, preclinical models, chemotherapy and radiotherapy interactions/combinations of chemotherapy and radiotherapy, and other combination treatments with the anti-tumor immune response.
Germline homozygosity and allelic imbalance of HLA-I are common in esophagogastric adenocarcinoma and impair the repertoire of immunogenic peptidesMaria Alejandra Garcia-Marquez, Martin Thelen, Eugen Bauer, Lukas Maas, Kerstin Wennhold, Jonas Lehmann, Diandra Keller, Miloš Nikolić, Julie George, Thomas Zander, Wolfgang Schröder, Philipp Müller, Ali M Yazbeck, Christiane Bruns, Roman ThomasSee the full list of authors
17 April 2024
Tetracyclines enhance antitumor T-cell immunity via the Zap70 signaling pathwayMari Tone, Kota Iwahori, Michinari Hirata, Azumi Ueyama, Akiyoshi Tani, Jun-Ichi Haruta, Yoshito Takeda, Yasushi Shintani, Atsushi Kumanogoh, Hisashi Wada
15 April 2024
Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cellsSarah Ducellier, Mélanie Demeules, Boris Letribot, Massimiliano Gaetani, Chloé Michaudel, Harry Sokol, Abdallah Hamze, Mouad Alami, Mégane Nascimento, Sébastien Apcher
11 April 2024
Type III interferon inhibits bladder cancer progression by reprogramming macrophage-mediated phagocytosis and orchestrating effective immune responsesBo Wang, Bingkun Zhou, Junyu Chen, Xi Sun, Wenjuan Yang, Tenghao Yang, Hao Yu, Peng Chen, Ke Chen, Xiaodong Huang, Xinxiang Fan, Wang He, Jian Huang, Tianxin Lin
8 April 2024
Targeting PARG induces tumor cell growth inhibition and antitumor immune response by reducing phosphorylated STAT3 in ovarian cancerAntons Martincuks, Chunyan Zhang, Theresa Austria, Yi-Jia Li, Rui Huang, Nicole Lugo Santiago, Adrian Kohut, Qianqian Zhao, Rosemarie Martinez Borrero, Binghui Shen, Mihaela Cristea, Edward W Wang, Mihae Song, Lorna Rodriguez-Rodriguez, Hua Yu
5 April 2024
Blocking senescence and tolerogenic function of dendritic cells induced by γδ Treg cells enhances tumor-specific immunity for cancer immunotherapyFusheng Si, Xia Liu, Yan Tao, Yuanqin Zhang, Feiya Ma, Eddy C Hsueh, Sidharth V Puram, Guangyong Peng
5 April 2024
Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cellsJordon M Inkol, Michael J Westerveld, Shayla G Verburg, Scott R Walsh, Jodi Morrison, Karen L Mossman, Sarah M Worfolk, Kaslyn LF Kallio, Noah J Phippen, Rebecca Burchett, Yonghong Wan, Jonathan Bramson, Samuel T Workenhe
4 April 2024
Inhibition of IL-25/IL-17RA improves immune-related adverse events of checkpoint inhibitors and reveals antitumor activityXizi Hu, Shoiab M Bukhari, Carly Tymm, Kieran Adam, Shalom Lerrer, Brian S Henick, Robert J Winchester, Adam Mor
21 March 2024
Circular RNA as a source of neoantigens for cancer vaccinesYi Ren, Thamizhanban Manoharan, Beijia Liu, Cyrus Zai Ming Cheng, Bei En Siew, Wai-Kit Cheong, Kai Yin Lee, Ian Jse-Wei Tan, Bettina Lieske, Ker-Kan Tan, Gloryn Chia
19 March 2024
BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1Young-Seung Kim, Seung-Hoon Lee, Andrew H Park, Chunai Wu, Bong-Ki Hong, Hyunjin Jung, Steven H Lin, Stephen S Yoo
14 March 2024