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Research Article
Human double negative T cells target lung cancer via ligand-dependent mechanisms that can be enhanced by IL-15

Authors

  • Junlin Yao Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada Present address: Sir Run Run Shaw Hospital, College of MedicineZhejiang University Hangzhou China PubMed articlesGoogle scholar articles
  • Dalam Ly Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Dzana Dervovic Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada Present address: Department of Systems Biology, Mount Sinai Hospital Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Linan Fang Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Jong Bok Lee Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Hyeonjeong Kang Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Yu-Hui Wang Princess Margaret Cancer CentreUniversity Health Network Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Nhu-An Pham Princess Margaret Cancer CentreUniversity Health Network Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Hongming Pan Sir Run Run Shaw Hospital, College of MedicineZhejiang University Hangzhou China PubMed articlesGoogle scholar articles
  • Ming-Sound Tsao Princess Margaret Cancer CentreUniversity Health Network Toronto Ontario Canada Department of Laboratory Medicine and PathobiologyUniversity of Toronto Toronto Ontario Canada PubMed articlesGoogle scholar articles
  • Li Zhang Toronto General Hospital Research InstituteUniversity Health Network Toronto Ontario Canada Department of ImmunologyUniversity of Toronto Toronto Ontario Canada Department of Laboratory Medicine and PathobiologyUniversity of Toronto Toronto Ontario Canada University Health NetworkPrincess Margaret Cancer Research Tower 101 College St. Rm 2-807 M5G 1L7 Toronto Ontario Canada PubMed articlesGoogle scholar articles
  1. ↵k 416-581-7521 lzhang{at}uhnresearch.ca
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Citation

Yao J, Ly D, Dervovic D, et al
Human double negative T cells target lung cancer via ligand-dependent mechanisms that can be enhanced by IL-15
Journal for ImmunoTherapy of Cancer 2019;7:17. doi: 10.1186/s40425-019-0507-2

Publication history

  • Received July 23, 2018
  • Accepted January 13, 2019
  • First published January 22, 2019.
Online issue publication 
January 08, 2022

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.