Immune phenotype

Increased CTLA-4⁺ T cells and an increased ratio of monocytes with loss of class II (CD14⁺ HLA-DR^lo/neg) found in aggressive pediatric sarcoma patients
Pooja Hingorani, Mary L. Maas, Michael P. Gustafson, Paul Dickman, Roberta H. Adams, Masayo Watanabe, Francis Eshun, James Williams, Matthew J. Seidel, Allan B. Dietz

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (1) 35; DOI: 10.1186/s40425-015-0082-0
Pharmacological inactivation of PI3Kδ in the tumor microenvironment enhances efficacy of other immunotherapeutic agents
Liang-Chuan S Wang, Holly Koblish, Michael Hansbury, Yue Zhang, Gengjie Yang, Timothy Burn, Paul Waeltz, Mark Rupar, Eddy Yue, Brent Douty, Thomas Maduskuie, Nikoo Falahatpisheh, Yun-Long Li, Andrew P Combs, Gregory Hollis, Reid Huber, Peggy Scherle

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P377; DOI: 10.1186/2051-1426-3-S2-P377

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