Immunotherapy Biomarkers

EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma
Jan H Frenking, Xiang Zhou, Vivien Wagner, Thomas Hielscher, Joseph Kauer, Elias K Mai, Mirco J Friedrich, Christian S Michel, Marina Hajiyianni, Iris Breitkreutz, Patrick Costello, Omar Nadeem, Niels Weinhold, Hartmut Goldschmidt, Anita Schmitt, Thomas Luft, Michael Schmitt, Carsten Müller-Tidow, Max Topp, Hermann Einsele, Peter Dreger, Nikhil C Munshi, Adam S Sperling, Leo Rasche, Sandra Sauer, Marc S Raab

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009220; DOI: 10.1136/jitc-2024-009220
A multicenter, randomized, non-comparative, phase II study of nivolumab ± ipilimumab for patients with metastatic sarcoma (Alliance A091401): expansion cohorts and correlative analyses
Nathan D Seligson, James L Chen, Austin C Goodrich, Brian A Van Tine, Jordan D Campbell, Allison L Richards, Cristina R Antonescu, David A Liebner, Mohammed M Milhem, Howard Streicher, William D Tap, Gary K Schwartz, Suzanne George, Sandra P D'Angelo

Journal for ImmunoTherapy of Cancer Sep 2024, 12 (9) e009472; DOI: 10.1136/jitc-2024-009472
Endosialin-positive CAFs promote hepatocellular carcinoma progression by suppressing CD8⁺ T cell infiltration
Lunbiao Gan, Tong Lu, Yu Lu, Hongtao Song, Jiayu Zhang, Keying Zhang, Shiqi Lu, Xinjie Wu, Fengze Nie, Sijia Di, Donghui Han, Fa Yang, Weijun Qin, Weihong Wen

Journal for ImmunoTherapy of Cancer Sep 2024, 12 (9) e009111; DOI: 10.1136/jitc-2024-009111
Intratumoral CXCL13⁺ CD160⁺ CD8⁺ T cells promote the formation of tertiary lymphoid structures to enhance the efficacy of immunotherapy in advanced gastric cancer
Jiawei Wang, Yuan Liang, Ao Xue, Jian Xiao, Xinyu Zhao, Shuqing Cao, Pengyu Li, Jiacheng Dong, Yuan Li, Zekuan Xu, Li Yang

Journal for ImmunoTherapy of Cancer Sep 2024, 12 (9) e009603; DOI: 10.1136/jitc-2024-009603
Angiotensin receptor blocker attacks armored and cold tumors and boosts immune checkpoint blockade
Jie Mei, Jiahui Chu, Kai Yang, Zhiwen Luo, Jiayue Yang, Junying Xu, Qing Li, Yan Zhang, Qinglin Zhang, Mengyun Wan, Ningyi Xue, Junli Ding, Yichao Zhu, Yun Cai, Yongmei Yin

Journal for ImmunoTherapy of Cancer Sep 2024, 12 (9) e009327; DOI: 10.1136/jitc-2024-009327
Non-invasive multimodal CT deep learning biomarker to predict pathological complete response of non-small cell lung cancer following neoadjuvant immunochemotherapy: a multicenter study
Guanchao Ye, Guangyao Wu, Yu Qi, Kuo Li, Mingliang Wang, Chunyang Zhang, Feng Li, Leonard Wee, Andre Dekker, Chu Han, Zaiyi Liu, Yongde Liao, Zhenwei Shi

Journal for ImmunoTherapy of Cancer Sep 2024, 12 (9) e009348; DOI: 10.1136/jitc-2024-009348
Tumor microenvironment biomarkers predicting pathological response to neoadjuvant chemoimmunotherapy in locally advanced esophageal squamous cell carcinoma: post-hoc analysis of a single center, phase 2 study
Tingting Feng, Qian Li, Rui Zhu, Chang Yu, Liwei Xu, Lisha Ying, Canming Wang, Weiming Xu, Jinchao Wang, Jing Zhu, Minran Huang, Chenyang Xu, Jiaoyue Jin, Xiaotian Zhang, Tingting Lu, Ying Yang, Changbin Zhu, Qixun Chen, Dan Su

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e008942; DOI: 10.1136/jitc-2024-008942
Targeting Gsk3a reverses immune evasion to enhance immunotherapy in hepatocellular carcinoma
Xin Zheng, Luyu Yang, Xiaotian Shen, Junjie Pan, Yiran Chen, Jixuan Chen, Hao Wang, Jiaqi Meng, Zhenchao Chen, Sunzhe Xie, Yitong Li, Bolun Zhu, Wenwei Zhu, Lunxiu Qin, Lu Lu

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009642; DOI: 10.1136/jitc-2024-009642
Gene panel predicts neoadjuvant chemoimmunotherapy response and benefit from immunotherapy in HER2-negative breast cancer
Xunxi Lu, Zongchao Gou, Hong Chen, Li Li, Fei Chen, Chunjuan Bao, Hong Bu

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009587; DOI: 10.1136/jitc-2024-009587
Blockade of glucose-6-phosphate dehydrogenase induces immunogenic cell death and accelerates immunotherapy
Motoki Nakamura, Tetsuya Magara, Maki Yoshimitsu, Shinji Kano, Hiroshi Kato, Keisuke Yokota, Katsuhiro Okuda, Akimichi Morita

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e008441; DOI: 10.1136/jitc-2023-008441

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